Your Outsourcing Partner for Protein Research and Production Services

To meet the needs of our clients, Exon provides protein characterization of our expressed protein to insure the quality of recombinant protein.

Recombinant Protein Expression

Exon BioSystems is a protein contract research and production services company specializing in recombinant protein expression, protein purification, and protein characterization.

Antibody Engineering

Additional areas of expertise include assay development of G-protein coupled receptor, recombinant vaccine development and recombinant antibody production.

Biologics

Exon BioSystems is a protein contract research and production services company specializing in recombinant protein expression, protein purification, and protein characterization.

Molecular Biology Services

cDNA Library Construction, Normalization and Screening

From hundreds of thousands of protein molecules, picking up one that is related to a particular biological phenomenon is a challenging task. To help researchers accomplish this task, we have developed proprietary technologies to construct cDNA libraries especially for this purpose. The cDNA libraries we constructed have an extraordinary complexity, a high percentage of full length clones, and high expression efficiency. With such libraries plus our systematic screening techniques and experience, we can help researchers pick up the cDNA clones which encode the proteins they are looking for.

The following are the cDNA library services we offer:
  • Construction of cDNA libraries from tissues, cells (1 million), total RNA (10 mg), or mRNA (200 ng). cDNA is directionally cloned into an expression plasmid without being digested by restriction enzymes. Our standard libraries contain more than 3 million primary clones and no PCR is used during construction to avoid PCR related artifacts. Services for construction of large insert cDNA libraries are available.
  • Normalization of cDNA libraries. The normalization procedure will reduce the abundance of the cDNA clones of the house-keeping genes 10 to 200 fold.
  • cDNA library screening. We use functional screening to identify the cDNA clones, which are related to particular biological phenomena from cDNA libraries.

We charge $3,990-$4,490 for a standard cDNA library and $7,190 for normalization.




For more information please call _858-457-1920 or e-mail us at: info @ exonbio.com, or use our contact page: Contact